The newly developed LaChromUltra II column is the longest UHPLC column at 250 mm in length. When used together with the reduced volume system ChromasterUltra Rs, it produces an exceptional high-separation performance.
The combination of this column and the ChromasterUltra Rs enables system pressure tolerance of 140 MPa with 50,000 or more theoretical plates per column.
A total-reflection capillary flow cell is incorporated into the diode array detector to answer to the increasing need for high-sensitivity analysis of hazardous substances, genotoxic impurities, etc. A high-sensitivity flow cell with an optical path length of 65 mm is also available. In addition to the capability of high-sensitivity analysis, carryover is reduced through the use of a double-corkscrew mixer.
The diode array detector (DAD) exhibits low noise and low drift, achieved through the use of a new optical system providing optimal conditions for high-sensitivity analysis. The optional high-sensitivity flow cell (optical path length of 65 mm) further enhances sensitivity; about a tenfold increase is obtained compared with our previous model (LaChromUltra), thus enabling high-sensitivity applications including impurities from side reactions, genotoxic impurities, etc.
The acquisition of impurity profiles during all stages of synthesis and in raw materials used in medicines and chemicals, intermediate byproducts, and finished drugs are examples of useful applications.
The binary pump is equipped with the latest design in microfluidic double-corkscrew mixers.
An efficient mixing is attained even for a low volume, resulting in a baseline that is extremely stable during gradient analysis, enabling higher-sensitivity analysis.
Structure of the double-corkscrew mixer:
Repeated branching and merging of channels within the mixer provide effective solvent mixing (mixer volume of 55 µL).
| Column | LaChromUltra II C18(1.9 µm) 2.0 mm I.D.×50 mm L. |
|---|---|
| Eluent | A)0.1% TFA/H2O(v/v) B)0.1% TFA/CH3CN(v/v) A/B=50/50 |
| Flow rate | 0.500 mL/min |
| Detection | UV 214 nm |
Low carryover (0.001% or less) is attained via the optimized injection port structure.
All modules can be controlled from the Graphical User Interface (GUI) controller.
The GUI is comprised of a color LCD monitor (5.7-inch color TFT display with LED back-light) and a touch panel made for easy viewing and simple operation.
Up to 10 programs including a timer function, pre-analysis tasks (Wakeup), and post-analysis tasks (Sleep) can be created for a system.
The GUI controller enables you to check the status of consumables usage for all units that are connected to the system.
Hitachi’ s own Moment Enhancing Mechanism (MEM) column fitting is a simple but exciting new development. The finger-tight piping integral fitting, which has a very small dead volume, is capable of safely tolerating system pressures as high as 140 MPa.
MEM column fitting
A view of the operation of attaching a column
Hitachi’s general-purpose atomic force microscope, Model AFM5100N, features superior ease of use, a wide range of capabilities, and extraordinary performance.
The PP3006 CoolLok offers rapid cryo transfer and cryo temperature observation of specimens for SEM, FIB/SEM, beamline or other vacuum systems.
The HDV 632 is a fully automated Vacuum Distillation Analyzer, which offers highest flexibility for the user. It can measure samples up to 650C AET.
ULTRAPOL End & Edge Polisher has been designed to provide accurate lapping and polishing for research and industrial applications. Several thousand of these units are already assisting users in a wide range of technical disciplines.
With the 360 ES series Precision balances, Precisa is setting new standards: innovative, high-tech instrumentation which includes the latest technical developments, unique performance features, best user-interface and the most modern design to establish the 360 ES series as the very bench-mark for modern laboratory technology.
Precisa offers a very compact balance while simultaneously meeting new challenges for a durable and economical ‘use anywhere’ balance. The models of the BJ series (165 BJ) were developed with exactly these goals in mind.
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